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ABN407 Anti-GLUT9 Antibody

Detect GLUT9 using this Anti-GLUT9 Antibody validated for use in western blotting & IHC (Paraffin).

Anti-GLUT9 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience Research Sub-Category: Signaling Neuroscience Gene Symbol: SLC2A9, GLUT9 UniProt Number: Q9NRM0
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ABN407
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, MWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN407
      DescriptionAnti-GLUT9 Antibody
      Alternate Names
      • Solute carrier family 2, facilitated glucose transporter member 9
      • Glucose transporter type 9
      • GLUT-9
      Background InformationGLUT9, also known as Glucose transporter type 9 or GLUT-9, and encoded by the gene SLC2A9/GLUT9, is a member of the sugar transport family that primarily transports urate and fructose; GLUT9 does also transport glucose but at a lower rate than its preferred sugars. GLUT9 also plays a role in urate reabsorption by the proximal tubules of the kidney. GLUT9 is localized to the plasma membrane. GLUT9 is most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. GLUT9 is also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Defects in GLUT9 may be associated with Hypouricemia renal 2 (RHUC2) a disorder characterized by impaired uric acid reabsorption at the apical membrane of proximal renal tubule cells, and high urinary urate excretion.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect GLUT9 using this Anti-GLUT9 Antibody validated for use in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected GLUT9 in human cerebellum and hindbrain tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human GLUT9.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody is expected to recognize both known isoforms of GLUT9.
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SLC2A9
      • GLUT9
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~62 kDa observed. Uniprot describes 2 isoforms at 59 kDa (isoform 1) and 55 kDa (isoform 2).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

      Western Blotting Analysis: 0.2 µg/mL of this antibody detected GLUT9 in 10 µg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABN407 04053252945694