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MABS1694 Anti-FABP2 Antibody, clone 4F6.1

Detect FABP2 using this mouse monoclonal Anti-FABP2 Antibody, clone 4F6.1, Cat. No. MABS1694, validated for use in Immunohistochemistry (Paraffin) and Western Blotting.

Anti-FABP2 Antibody, clone 4F6.1: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Signaling Gene Symbol: FABP2, FABPI UniProt Number: P12104
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MABS1694
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, M, HIH(P), WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS1694
      DescriptionAnti-FABP2 Antibody, clone 4F6.1
      Alternate Names
      • Fatty acid-binding protein
      • intestinal
      • Fatty acid-binding protein 2
      • I-FABP
      • Intestinal-type fatty acid-binding protein
      Background InformationFatty acid-binding protein, intestinal (UniProt P12104; also known as Fatty acid-binding protein 2, I-FABP, Intestinal-type fatty acid-binding protein) is encoded by the FABP2 (also known as FABPI) gene (Gene ID 2169) in human. The intracellular lipid-binding protein (iLBP) multigene family includes 12 fatty acid-binding protein (FABPs), 4 retinol-binding proteins (RBPs) and 2 cellular retinoic acid-binding proteins (CRABPs). FABPs are 14-16 kDa cytosolic proteins that bind fatty acids (FAs) and other hydrophobic ligands, such as eicosanoids and retinoids. FABPs are either numbered by the Hertzel and Bernlohr nomenclature to indicate their chronological order of discovery or named according to the tissue where each FABP was first isolated. In addition to transporting and sequestering long-chain FAs, eicosanoids, bile salts, and other hydrophobic ligands for storage and metabolism, FABPs are long recognized for their role in gene transcription regulation via lipid-mediated activation of nuclear hormone receptors (NHRs). FABP1 and FABP2, for example, are shown to bind a range of PPAR agonists, including long chain fatty acids (LCFA) and drugs. FABPs play differential and ligand-specific roles in NHR activation, and the patterns of drug interaction with intracellular binding proteins such as FABPs may govern tissue-specific actions of drugs that target NHRs.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect FABP2 using this mouse monoclonal Anti-FABP2 Antibody, clone 4F6.1, Cat. No. MABS1694, validated for use in Immunohistochemistry (Paraffin) and Western Blotting.
      Key Applications
      • Immunohistochemistry (Paraffin)
      • Western Blotting
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative detected FABP2 in human small intestine and rat colon tissue sections.

      Western Blotting Analysis: A 1:1,000 dilution from a representative detected FABP2 in 10 µg of human small intestine tissue lysate.
      Biological Information
      ImmunogenGST-tagged recombinant human FABP2.
      Clone4F6.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone 4F6.1 targets an epitope conserved among human, mouse, and rat species.
      IsotypeIgG1κ
      Species Reactivity
      • Rat
      • Mouse
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FABP2
      • FABPI
      Purification MethodProtein G purified.
      UniProt Number
      Molecular Weight~15 kDa observed. 15.11 kDa (human), 14.99 kDa (mouse & rat) calculated (Met1 removed). Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse small intestine tissue lysate.

      Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP2 in 10 µg of mouse small intestine tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      MABS1694 04054839056260