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AB15468 Anti-Choline Acetyltransferase Antibody

Anti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IC, IH.

Anti-Choline Acetyltransferase Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors, Neuronal & Glial Markers Gene Symbol: CHAT, ChAT, CMS1A2, CHOACTase, CMS1A, EC 2.3.1.6 UniProt Number: P28329
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AB15468
500 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MICC, IHCChAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15468
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Choline Acetyltransferase Antibody
      Alternate Names
      • ChAT
      Product Information
      FormatAffinity Purified
      PresentationLiquid in PBS, pH 7.2 with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IC, IH.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry: 1:1,000-1:2,000 using 2% paraformaldehyde fixed tissue.

      Immunocytochemistry: 1:1,000-1:2,000 using 2% paraformaldehyde fixed cells.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide corresponding to human/mouse ChAT protein.
      HostChicken
      SpecificityCholine acetyltransferase [ChAT]
      Species Reactivity
      • Mouse
      Species Reactivity NoteOther species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryCholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein.
      Gene Symbol
      • CHAT
      • ChAT
      • CMS1A2
      • CHOACTase
      • CMS1A
      • EC 2.3.1.6
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
      SIZE: 748 amino acids; 82568 Da
      DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
      SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size500 µL
      Global Trade Item Number
      Bestellnummer GTIN
      AB15468 04053252401275