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MABF505 Anti-CAMK4, clone 8C5B8 Antibody

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MABF505
100 µL  
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      Übersicht

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, IF, ELISAMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF505
      DescriptionAnti-CAMK4, clone 8C5B8 Antibody
      Alternate Names
      • Calcium/calmodulin-dependent protein kinase type IV
      • CaMK IV
      • CAMK4
      Background InformationCalcium/calmodulin-dependent protein kinase type IV (CaMK IV), also known as CaM kinase-GR, and encoded by the gene name CAMK4 or CAMK or CAMK-GR or CAMKIV, is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. CAMK4 is localized in hippocampal neuron nuclei and is associated with chromatin and the nuclear matrix in spermatids. Expression in CAMK4 can be found in brain, thymus, CD4 T-cells, testis, and epithelial ovarian cancer tissue. CAMK4 can be phosphorylated by CaMKK1 and CaMKK2 on Thr200 and dephosphorylated by protein phosphatase 2A.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal in PBS containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-CAMK4, clone 8C5B8 Antibody is validated for use in western blotting, IHC, immunofluorescence & ELISA for the detection of CAMK4.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      • ELISA
      Application NotesImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected CAMK4 in ovarian and rectum cancer tissues.

      Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected CAMK4 in HepG2 cells.

      ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human CAMK4 expressed in E. Coli
      Clone8C5B8
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • CAMK4
      • CAMK
      • CAMK-GR
      • CAMKIV
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~57 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in SK-N-SH, Raji and HeLa cell lysates.

      Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected CAMK4 in SK-N-SH, Raji and HeLa cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      MABF505 04053252957154