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ABC349 Anti-ABCA7 Antibody

Anti-ABCA7 Antibody is a highly specific rabbit polyclonal antibody, that targets ABCA7 & has been tested in western blotting & ICC.

Anti-ABCA7 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ABCA7 UniProt Number: Q8IZY2
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ABC349
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC349
      DescriptionAnti-ABCA7 Antibody
      Alternate Names
      • ATP-binding Cassette Sub-family A (ABC1) member 7
      • ABC1
      • ABC Transporter 1
      • ATP-binding Cassette 1
      • ATP-binding Cassette Transporter 1
      • CERP
      • ABCA-SSN
      • Autoantigen SS-N
      • Macrophage ABC transporter
      • ABCA7
      Background InformationATP-binding cassette sub-family A member 7 (ABCA7), also known as ABCA-SSN and Macrophage ABC transporter, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. It uses ATP hydrolysis to catalyze the transport of various molecules across cell membranes. ABCA7 is involved in phagocytosis by macrophages of apoptotic cells, binds to APOA1, may function in phospholipid and cholesterol efflux from cells, and may regulate cellular ceramide homeostasis during keratinocyte differentiation The high ABCA7 expression levels in peripheral leukocytes, thymus, spleen and bone marrow indicates a role in the immune system lipid homeostasis. ABCA1 is also highly expressed in fetal tissues, especially the liver.
      References
      Product Information
      FormatAffinity Purified
      Control
      • HEK293 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ABCA7 Antibody is a highly specific rabbit polyclonal antibody, that targets ABCA7 & has been tested in western blotting & ICC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 5 µg/mL from a representative lot detected ABCA7 in HEK293 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ABCA7.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ABCA7
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~234 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~219 kDa and ~234 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293 cell lysate.

      Western Blotting Analysis: 1µg/mL of this antibody detected ABCA7 in 15 µg of HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABC349 04053252905117