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238900 4-Cyano-3-methylisoquinoline

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
161468-32-2C₁₁H₈N₂

Preis & Verfügbarkeit

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238900-5MG
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      Glasflasche 5 mg
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      Description
      OverviewA potent, cell-permeable, reversible, and specific inhibitor of protein kinase A (IC50 = 30 nM). Inhibition is competitive with respect to ATP. Shows only weak inhibitory activities against Ca2+-dependent protein kinase (CDPK), MLCK, PKC, and cyclic nucleotide-binding phosphatase.
      Catalogue Number238900
      Brand Family Calbiochem®
      SynonymsPKA Inhibitor XI
      References
      ReferencesLu, Z.X., et al. 1996. Biol. Chem. Hoppe Seyler 377, 373.
      Product Information
      CAS number161468-32-2
      ATP CompetitiveY
      FormWhite solid
      Hill FormulaC₁₁H₈N₂
      Chemical formulaC₁₁H₈N₂
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKA
      Primary Target IC<sub>50</sub>30 nM against protein kinase A
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      238900-5MG 04055977216653

      Documentation

      4-Cyano-3-methylisoquinoline SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      4-Cyano-3-methylisoquinoline Analysenzertifikate

      TitelChargennummer
      238900

      Literatur

      Übersicht
      Lu, Z.X., et al. 1996. Biol. Chem. Hoppe Seyler 377, 373.

      Broschüre

      Titel
      Inhibitor Sourcebook 3rd Edition
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-April-2011 RFH
      SynonymsPKA Inhibitor XI
      DescriptionA potent, cell-permeable, specific inhibitor of protein kinase A (PKA; IC50 = 30 nM). Inhibition is competitive with respect to ATP. Shows only weak inhibitory activities against Ca2+-dependent protein kinase (CDPK), MLCK, PKC, and cyclic nucleotide-binding phosphatase (Pase).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number161468-32-2
      Chemical formulaC₁₁H₈N₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesLu, Z.X., et al. 1996. Biol. Chem. Hoppe Seyler 377, 373.