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Pellicon® XL 50 Ultrafiltration Cassettes

True linear scalability with UF membranes with the same flow path and channel height as larger Pellicon® 2 cassettes. The Pellicon XL 50 allows process development and scaling studies.

Descripción

Especificaciones

Información para pedidos

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Biomax, poliétersulfona Borrar Clasificación y Filtrado Show Filter
Número de referenciaCódigo del filtroLímite de peso molecular nominal (NMWL)
PXB005A50Biomax 5 5 kDa Precios y disponibilidad
PXB008A50Biomax 8 8 kDa Precios y disponibilidad
PXB010A50Biomax 10 10 kDa Precios y disponibilidad
PXB030A50Biomax 30 30 kDa Precios y disponibilidad
PXB050A50Biomax 50 50 kDa Precios y disponibilidad
PXB100C50Biomax 100 100 kDa Precios y disponibilidad
PXB300C50Biomax 300 300 kDa Precios y disponibilidad
PXB500C50Biomax 500 500 kDa Precios y disponibilidad
PXB01MC50Biomax 1000 1000 kDa Precios y disponibilidad

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Ultracel, celulosa regeneradaBorrar Clasificación y Filtrado Show Filter
Número de referenciaCódigo del filtroLímite de peso molecular nominal (NMWL)
PXC005C50PLCCC 5 kDa Precios y disponibilidad
PXC010C50PLCGC 10 kDa Precios y disponibilidad
PXC030C50PLCTK 30 kDa Precios y disponibilidad
PXC300C50PLCMK 300 kDa Precios y disponibilidad
PXC01MC50PLCXK 1000 kDa Precios y disponibilidad
PXC100C50PLCHK 100 kDa Precios y disponibilidad

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AccesoriosBorrar Clasificación y Filtrado Show Filter
Número de referenciaDescripción
XXPXLFTKTAdaptadores y tubos Precios y disponibilidad
XXPXLSTNDSoporte para Pellicon Precios y disponibilidad
XX42RES01Depósito 500 ml para LabScale Precios y disponibilidad
XXPXLGAGEManómetro 0-4,2 bar con conexiones Precios y disponibilidad

Los filtros Pellicon XL se suministran en envase individual. Los adaptadores y tubos son incluidos con cada cassette.

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Documentation

Referencias bibliográficas

Visión general referencias
Scaling Up with Tangenital Flow Filtration
Campbell, Melissa; Coons, Elizabeth
GEN; v. 21, no. 16; Sept. 15, 2001, p. 60  2001

Linear Scale Ultrafiltration
van Reis, Robert, Elizabeth M. Goodrich, Christine L. Yson, Leah N. Frautschy, Stephen Dzengeleski, and Herb Lutz
Biotechnology & Bioengineering (September 1997): 737-746.  1997

Clean-Water Permeability as a Determinant of Cleaning Efficacy in Tangential-Flow Filtration Systems
Michaels, Stephen L.; RP016
RP016  1993

Validation of Tangential Flow Filtration (TFF) Systems
Michaels, Stephen L.
Journal of Parenteral Science and Technology (Sept/Oct 1991).  1991

Preguntas frecuentes

PreguntaRespuesta
What is the sample volume range for the Pellicon II Mini system?The Pellicon II Mini system is capable of volumes in the approximate range of 1- 50 L concentrating down to 100 mL. More or less volume can be processed depending on the individual needs of the operation, ie. process time, sensitivity of product, etc.
What is the part number for the Gauge Kit that is used with the Pellicon XL?Gauge Kit for Pellicon XL Device (0-60 psi):
Part number XXPXLGAGE, 1 per kit. Includes an inlet pressure gauge and t-fitting. This gauge is recommended when the Pellicon is used in the absence of a Labscale TFF system in order to ensure that the pressure on the tubing is known and not allowed to exceed it's recommended maximum.
Can I use TFF systems to separate two proteins based on a significant difference in their respective molecular weights?As a general rule ultrafiltration does not provide high efficiency separations of protein mixtures. However, it may be possible to effect this type of separation between two proteins that have at least 10 X difference in molecular weight and if there is an ultrafiltration membrane available with a NMWL rating between the molecular weight of the two proteins. These separations are also generally more successful with dilute protein solutions and if run at low pressure.

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Categorías

Biopharmaceutical Manufacturing > Downstream Processing > Ultrafiltration