Millipore Sigma Vibrant Logo

368059 Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Z-IETD-AFC, Caspase-8 Substrate II

View Products on Sigmaaldrich.com
368059
Ver precios y disponibilidad

Descripción

Replacement Information

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
368059-1MG
Comprobando disponibilidad...
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      		 Ampolla de plást. 1 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      —
      Solicitar precio
      		 —
      Description
      OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
      Catalogue Number368059
      Brand Family Calbiochem®
      SynonymsZ-IETD-AFC, Caspase-8 Substrate II
      References
      ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
      Product Information
      CAS number219138-02-0
      ATP CompetitiveN
      FormWhite lyophilized solid
      Hill FormulaC₃₇H₄₂F₃N₅O₁₃
      Chemical formulaC₃₇H₄₂F₃N₅O₁₃
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      368059-1MG 07790788049621

      Documentation

      Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      368059

      Referencias bibliográficas

      Visión general referencias
      Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

      Folleto

      Cargo
      Caspases and other Apoptosis Related Tools Brochure
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-July-2008 RFH
      SynonymsZ-IETD-AFC, Caspase-8 Substrate II
      DescriptionA fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
      FormWhite lyophilized solid
      CAS number219138-02-0
      Chemical formulaC₃₇H₄₂F₃N₅O₁₃
      Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
      Purity≥97% by HPLC
      SolubilityDMSO (1 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.