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109272 Papanicolaou's solution 3b polychromatic solution EA 50

for cytology

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
109272
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1092720500
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      		 Plastic bottle 500 ml
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      1092721000
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          		 Plastic bottle 1 l
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          1092721022
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              1092722500
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                  		 Plastic bottle 2.5 l
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                  Description
                  Catalogue Number109272
                  DescriptionPapanicolaou's solution 3b polychromatic solution EA 50
                  OverviewPapanicolaou’s solution 3b polychromatic solution EA 50 - for cytology, is a ready-to-use solution used for human-medical cell diagnosis and serve the purpose of the cytological investigation of sample material of human origin, for example, gynecological and clinico-cytological specimen materials. Papanicolaou’s technique is the most used staining procedure for cytological specimen is and is intended for the the staining of exfoliative cells in cytological specimens. In the first step, the cell nuclei are stained either progressively or regressively with a hematoxylin solution, (Hematoxylin solution modified acc.to Gill II, (Cat.no. 105175), Papanicolaou’s solution 1a Harris hematoxylin solution, (Cat.no. 109253) or Papanicolaou’s solution 1b Hematoxylin solution S, (Cat.no. 109254)). Nuclei are stained blue to dark violet. In the progressive hematoxylin staining method, staining is carried out to the endpoint, after which the slide is blued in tapwater. With the regressive method the material is over-stained and the excess of staining solution is removed by acid rinsing steps, followed by the bluing step. The structures of nuclei are more differentiated and better visible by the regressive method. The second staining step is cytoplasmic staining by orange staining solution (Papanicolaou’s solution 2b Orange II solution, Cat. no. 1106887 or Papanicolaou’s solution 2a Orange G solution (OG6), Cat. no. 106888), especially for demonstration of mature and keratinized cells. The target structures are stained orange in different intensities. In the third staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown, (Papanicolaou’s solution 3a polychromatic solution EA 31, (Cat.no 109271), Papanicolaou’s solution 3b polychromatic solution EA 50, (Cat.no. 109272), Papanicolaou’s solution 3c polychromatic solution EA 65(Cat.no. 109270), o Papanicolaou’s solution 3d polychromatic solution EA 65, (Cat.no.109269). The polychrome solution is used for demonstration of differentiation of squamous cells. Papanicolaou’s solution 3b polychromatic solution EA 50 gives a blue-green-pinkish staining result in clinical specimen material.
                  The 500 ml bottle provides 1500 - 2000 stainings. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
                  References
                  Product Information
                  HS Code3212 90 00
                  Quality LevelMQ400
                  Applications
                  Applicationfor cytology
                  Biological Information
                  Physicochemical Information
                  Density0.82 g/cm3 (20 °C)
                  Flash point17 °C
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Hazard Pictogram(s) Hazard Pictogram(s)
                  Hazard Pictogram(s)
                  Hazard Pictogram(s)
                  Hazard Statement(s)H225: Highly flammable liquid and vapour.
                  H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
                  H317: May cause an allergic skin reaction.
                  H319: Causes serious eye irritation.
                  H370: Causes damage to organs.
                  Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
                  P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
                  P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
                  P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
                  P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
                  P308 + P311: IF exposed or concerned: Call a POISON CENTER/doctor.
                  P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
                  Signal WordDanger
                  Storage class3 Flammable liquids
                  WGKWGK 2 obviously hazardous to water
                  Disposal1
                  Strongly contaminated halogen-free organic solvents: container A.
                  Safety Information
                  Categories of dangerhighly flammable, toxic
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at +15°C to +25°C.
                  Packaging Information
                  Transport Information
                  Declaration (railroad and road) ADR, RIDUN 1987 , 3, II
                  Declaration (transport by air) IATA-DGRUN 1987 , 3, II
                  Declaration (transport by sea) IMDG-CodeUN 1987 , 3, II
                  Supplemental Information
                  Specifications
                  Suitability for microscopy (Vaginal smear)passes test
                  Nucleiblue to dark violet
                  Cyanophilic Cytoplasm (basophilic)blue-green
                  Eosinophilic Cytoplasm (acidophilic)pink
                  Global Trade Item Number
                  Catalogue Number GTIN
                  1092720500 04022536112886
                  1092721000 04022536676685
                  1092721022 04022536707457
                  1092722500 04022536112909

                  Documentation

                  Required Licenses

                  Title
                  ANMAT

                  Papanicolaou's solution 3b polychromatic solution EA 50 SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Papanicolaou's solution 3b polychromatic solution EA 50 Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1092720500 Plastic bottlePDF Specification Document
                  1092721000 Plastic bottlePDF Specification Document
                  1092721022 Plastic bottlePDF Specification Document
                  1092722500 Plastic bottlePDF Specification Document

                  User Guides

                  Title
                  User Guide (IFU) - 109272

                  Related Products & Applications

                  Accessories (Primary)

                  Catalogue Number Description  
                  106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                  106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                  109253 Papanicolaou's solution 1a Harris' hematoxylin solution Show Pricing & Availability

                  Accessories (Secondary)

                  Catalogue Number Description  
                  106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                  106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                  109253 Papanicolaou's solution 1a Harris' hematoxylin solution Show Pricing & Availability

                  Related Products By: Application Facete

                  Clinical Cytology
                  Cytodiagnosis
                  Papanicolaou

                  Categories

                  IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents