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101587 L-Arginine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
74-79-3200-811-1C₆H₁₄N₄O₂174.2 g/molPh Eur,ChP,JP,USP

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1015871000
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      Description
      Catalogue Number101587
      SynonymsArg
      References
      Product Information
      CAS number74-79-3
      EC number200-811-1
      GradePh Eur,ChP,JP,USP
      Hill FormulaC₆H₁₄N₄O₂
      Molar Mass174.2 g/mol
      HS Code2925 29 19
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.1 g/cm3
      Melting Point223 - 224 °C (decomposition)
      pH value11.4 (100 g/l, H₂O, 20 °C)
      Vapor pressure<0.1 hPa (25 °C)
      Bulk density640 kg/m3
      Solubility148.7 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat > 5110 mg/kg
      Safety Information according to GHS
      RTECSCF1934200
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Categories of dangerirritant
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
      Identity (IR-spectrum)passes test
      Identity (TLC)passes test
      Identity (specific rotation)passes test
      Appearancewhite to almost white, crystalline powder or colorless crystals
      Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
      Appearance of solution (100 g/l, CO₂-free water)clear and colorless
      Transmittance of solution (100 g/l, water)≥ 98.0 %
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+25.5 to +28.5
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.9 to +27.9
      Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.3 to +27.7
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l,previously dried substance)+26.9 to +27.9
      pH (100 g/l, CO₂-free water)10.5 - 12.0
      Alkalinity (100 g/l, water)10.5 - 12.0
      Proteinspasses test
      Chloride (Cl)≤ 200 ppm
      Sulfate (SO₄)≤ 200 ppm
      Heavy metals (as Pb)≤ 10 ppm
      As (Arsenic)≤ 1 ppm
      Cu (Copper)*≤ 25 ppm
      Fe (Iron)≤ 10 ppm
      Mn (Manganese)≤ 25 ppm
      Mo (Molybdenum)*≤ 2.5 ppm
      Ni (Nickel)≤ 2 ppm
      Zn (Zinc)≤ 130 ppm
      Other amino acids (TLC)≤ 0.4 %
      Related substances (TLC)passes test
      Related Compounds, total (TLC)≤ 0.5 %
      Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
      Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
      Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
      Residual solvents (ICH Q3C)excluded by manufacturing process
      Sulfated ash (600 °C)≤ 0.1 %
      Loss on drying (105 °C; 3 h)≤ 0.30 %
      Bacterial endotoxins≤ 2.0 I.U./g
      Bacterial endotoxins (ChP)< 10.0
      Microbiological test (total aerobic microbial count (TAMC))≤ 10²
      Microbiological test (total yeast and mould count (TYMC))≤ 10¹
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph. Eur., ChP, JP, USP.
      Global Trade Item Number
      Catalogue Number GTIN
      1015871000 04022536901527

      Documentation

      Material Qualification Dossier

      TitleVersion
      9.1

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      L-Arginine SDS

      Title

      Safety Data Sheet (SDS) 

      L-Arginine Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1015871000 Plastic bottlePDF Specification Document

      Certificates

      Title