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137003 Citric acid monohydrate

cryst. EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP

Citric acid monohydrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

CAS #: 5949-29-1 EC Number: 201-069-1 Molar Mass: 210.14 g/mol Hill Formula: C₆H₈O₇ * H₂O Grade: Ph Eur,BP,ChP,JP,USP
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137003
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Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
5949-29-1201-069-1C₆H₈O₇ * H₂O210.14 g/molPh Eur,BP,ChP,JP,USP

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      Description
      Catalogue Number137003
      Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
      References
      Product Information
      CAS number5949-29-1
      EC number201-069-1
      GradePh Eur,BP,ChP,JP,USP
      Hill FormulaC₆H₈O₇ * H₂O
      Molar Mass210.14 g/mol
      HS Code2918 14 00
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.54 g/cm3 (20 °C)
      Flash point173.9 °C Not applicable
      Melting Point135 - 152 °C
      pH value1.8 (50 g/l, H₂O, 20 °C)
      Vapor pressure<1 Pa (25 °C)
      Bulk density800 - 1000 kg/m3
      Solubility880 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 3000 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H319: Causes serious eye irritation.
      H335: May cause respiratory irritation.
      Precautionary Statement(s)P261: Avoid breathing dust.
      P264: Wash skin thoroughly after handling.
      P271: Use only outdoors or in a well-ventilated area.
      P280: Wear eye protection/ face protection.
      P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      Signal WordWarning
      RTECSGE7810000
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Categories of dangerirritant
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Specifications
      Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
      Identity (IR-spectrum)passes test
      Identity (wet chemistry)passes test
      Appearancewhite to almost white or colorless crystals
      Appearance of solution (200 g/l; water)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
      Chloride (Cl)≤ 5 ppm
      Sulfate (SO₄)≤ 50 ppm
      Heavy metals (as Pb)≤ 5 ppm
      Al (Aluminium)≤ 0.2 ppm
      As (Arsenic)≤ 1 ppm
      Ca (Calcium)passes test
      Fe (Iron)≤ 10 ppm
      Oxalates (as C₂H₂O₄)≤ 360 ppm
      Oxalate (C₂H₂O₄) (ChP)passes test
      Residual solvents (ICH (Q3C))excluded by manufacturing process
      Readily carbonisable substancepasses test
      Sulfated ash (600 °C)≤ 0.05 %
      Water (according to Karl Fischer)7.5 - 9.0 %
      Total aerobic microbial count (TAMC)≤ 100 CFU/g
      Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
      Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
      Candida albicans (absent in 1 g)passes test
      Escherichia coli (absent in 1 g)passes test
      Pseudomonas aeruginosa (absent in 1 g)passes test
      Salmonella (absent in 10 g)passes test
      Staphylococcus aureus (absent in 1 g)passes test
      DNases (Exo- and endonucleases)not detectable
      RNasesnot detectable
      Bacterial endotoxins< 10

      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph. Eur., BP, ChP, JP, USP
      Global Trade Item Number
      Catalogue Number GTIN
      1370035000 04027269061432

      Documentation

      Material Qualification Dossier

      TitleVersion
      9.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      Citric acid monohydrate SDS

      Title

      Safety Data Sheet (SDS) 

      Citric acid monohydrate Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1370035000 Plastic bottlePDF Specification Document

      Certificates

      Title