Millipore Sigma Vibrant Logo

211200 CAPE - CAS 104594-70-9 - Calbiochem

A cell-permeable active component of propolis from honeybee hives.

CAPE - CAS 104594-70-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Caffeic Acid Phenethyl Ester, Synthetic

Primary Target: HIV-integrase
View Products on Sigmaaldrich.com
211200
View Pricing & Availability

Overview

Key Spec Table

CAS #Empirical Formula
104594-70-9C₁₇H₁₆O₄

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
211200-25MG
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 25 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Add To Favorites
      Description
      OverviewA cell-permeable active component of propolis from honeybee hives. Known to have antiviral, anti-inflammatory, and immunomodulatory properties. Has also recently been shown to act as a potent and specific inhibitor of NF-κB activation. An inhibitor of HIV-1 integrase activity. Inhibits the growth of different types of transformed cells. Has been reported to suppress lipid peroxidation. Inhibits ornithine decarboxylase, protein tyrosine kinase (PTK), and lipoxygenase activities. Also induces apoptosis in cloned rat embryo fibroblast (CREF) cells transformed by a number of different oncogenes.
      Catalogue Number211200
      Brand Family Calbiochem®
      SynonymsCaffeic Acid Phenethyl Ester, Synthetic
      References
      ReferencesNicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920.
      Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090.
      Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171.
      Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373.
      Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841.
      Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445.
      Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865.
      Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399.
      Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.
      Product Information
      CAS number104594-70-9
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₁₇H₁₆O₄
      Chemical formulaC₁₇H₁₆O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetHIV-integrase
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      211200-25MG 07790788048525