Millipore Sigma Vibrant Logo

178251 α₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem

α₁-Antitrypsin, CAS 9041-92-3, is a protease inhibitor of the serpin superfamily. Inhibits elastase, cathepsin G, and proteinase 3.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: α₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein

Primary Target: serine proteases
View Products on Sigmaaldrich.com
178251
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #
9041-92-3

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
178251-1MG
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Glass bottle 1 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Description
      OverviewA single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase. Inhibitor of neutrophil elastase, cathepsin G, and proteinase 3.
      Catalogue Number178251
      Brand Family Calbiochem®
      Synonymsα₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein
      References
      ReferencesCoakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33.
      Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.
      Product Information
      CAS number9041-92-3
      Activity≥75% inhibition with active-site titrated porcine trypsin using benzoyl-Arg-p-nitroanilide (Bz-Arg-pNA) as the substrate.
      ATP CompetitiveN
      FormSolid
      FormulationLyophilized from 300 mM NaCl, 30 mM sodium phosphate buffer, pH 6.5.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetserine proteases
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      178251-1MG 07790788059835

      Documentation

      α₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      α₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem Certificates of Analysis

      TitleLot Number
      178251

      References

      Reference overview
      Coakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33.
      Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-April-2008 RFH
      Synonymsα₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein
      DescriptionA single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues. Present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase.
      FormSolid
      FormulationLyophilized from 300 mM NaCl, 30 mM sodium phosphate buffer, pH 6.5.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number9041-92-3
      Purity≥95% by SDS-PAGE
      Activity≥75% inhibition with active-site titrated porcine trypsin using benzoyl-Arg-p-nitroanilide (Bz-Arg-pNA) as the substrate.
      SolubilityH₂O. Please refer to vial label for lot-specific volume prior to lyophilization.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
      Toxicity Standard Handling
      Merck USA index14, 719
      ReferencesCoakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33.
      Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.