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105995 (-)-Menthol

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
2216-51-5218-690-9C₁₀H₂₀O156.27 g/molPh Eur,BP,JP,USP

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1059951000
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      Description
      Catalogue Number105995
      Synonyms2-Isopropyl-5-methylcyclohexanol
      References
      Product Information
      CAS number2216-51-5
      EC number218-690-9
      GradePh Eur,BP,JP,USP
      Hill FormulaC₁₀H₂₀O
      Molar Mass156.27 g/mol
      HS Code2906 11 00
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Boiling point216 °C (1013 hPa)
      Density0.890 g/cm3 (20 °C)
      Flash point94 °C
      Melting Point>41.2 - 41.7 °C
      Vapor pressure0.19 hPa (25 °C)
      Bulk density450 kg/m3
      Solubility0.379 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 3300 mg/kg
      LD 50 dermalLD50 Rabbit > 5000 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H315: Causes skin irritation.
      H319: Causes serious eye irritation.
      Precautionary Statement(s)P264: Wash skin thoroughly after handling.
      P280: Wear protective gloves/ eye protection/ face protection.
      P302 + P352: IF ON SKIN: Wash with plenty of water.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      P332 + P313: If skin irritation occurs: Get medical advice/ attention.
      P337 + P313: If eye irritation persists: Get medical advice/ attention.
      Signal WordWarning
      RTECSOT0700000
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Categories of dangerirritant
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (JP)≥ 98.0 %
      Assay (USP)98.0 - 102.0 % (w/w)
      Identity (GC)passes test
      Purity (Ph Eur)≥ 99.0 % (a/a)
      Identity (wet chemistry)passes test
      Identity (specific rotation)passes test
      Appearance of solution (10 %; ethanol 96 %)passes test
      Acidity or alkalinitypasses test
      Melting range (lower value)≥ 41 °C
      Melting range (upper value)≤ 44 °C
      Melting point42 - 44 °C
      Spec. rotation (α 20/D; 10 %; ethanol (96 %))-51 - -48 °
      Spec. rotation (α 25/D; 10 %; ethanol (96 %))-51 - -45 °
      Spec. rotation (α 20/D; 10 %; ethanol (95 %))-51.0 - -45.0 °
      Nitromethane or Nitroethanepasses test
      Thymolpasses test
      Sum of impurities (Ph Eur)≤ 1.0 % (a/a)
      Largest impurity (USP)≤ 0.3 % (a/a)
      Sum of impurities (USP)≤ 2.0 % (a/a)
      Acetone (HS-GC)≤ 5000 ppm
      Methanol (HS-GC)≤ 3000 ppm
      Other residual solvents (ICH Q3C)excluded by the manufacturing process
      Evaporation residue≤ 0.05 %
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph Eur, BP, JP, USP
      Corresponds to Ph Eur, BP, JP, USP
      Global Trade Item Number
      Catalogue Number GTIN
      1059951000 04022536070858

      Documentation

      Material Qualification Dossier

      TitleVersion
      10.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      (-)-Menthol SDS

      Title

      Safety Data Sheet (SDS) 

      (-)-Menthol Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1059951000 Glass bottlePDF Specification Document

      Certificates

      Title