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1.06577

tri-Sodium phosphate dodecahydrate

EMPROVE® ESSENTIAL, NF, E 339

Synonym(s):

tri-Sodium phosphate dodecahydrate, Sodium phosphate tribasic, Trisodium phosphate

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About This Item

Empirical Formula (Hill Notation):
Na3O4P · 12H2O
CAS Number:
10101-89-0
Molecular Weight:
380.12
UNSPSC Code:
12352302
E Number:
E339
EC Index Number:
231-509-8
MDL number:
MFCD00149198
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agency

NF

Quality Segment

500

product line

EMPROVE® ESSENTIAL

form

solid

pH

12 (20 °C, 10 g/L in H2O)

mp

75 °C (Elimination of water of crystallisation)

solubility

285 g/L

density

1.62 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

[Na+].[Na+].[Na+].[P](=O)([O-])([O-])[O-].O.O.O.O.O.O.O.O.O.O.O.O

InChI

1S/3Na.H3O4P.12H2O/c;;;1-5(2,3)4;;;;;;;;;;;;/h;;;(H3,1,2,3,4);12*1H2/q3*+1;;;;;;;;;;;;;/p-3

InChI key

ASTWEMOBIXQPPV-UHFFFAOYSA-K

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium phosphate dodecahydrate is used as a buffering agent for liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Exclamation mark
GHS07

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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