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Merck

345812

G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 108321-42-2 - Calbiochem

Synonym(s):

G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 108321-42-2 - Calbiochem, G418, G 418, NMD Inhibitor I

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About This Item

Empirical Formula (Hill Notation):
C20H40N4O10 · 2H2SO4
CAS Number:
108321-42-2
Molecular Weight:
692.71
UNSPSC Code:
12352200
MDL number:
MFCD00058314

Key Documents

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SMILES string

[S](=O)(=O)(O)O.N([C@@H]1[C@H]([C@H](OC[C@@]1(O)C)O[C@@H]2[C@H]([C@@H]([C@H](C[C@H]2N)N)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3N)O)O)[C@H](O)C)O)O)C

InChI key

QNQZPJLBGRQFDD-ZMSORURPSA-N

assay

≥98% (TLC)

form

solution

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

clear colorless

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Potency: ≥730 µg/mg

Disclaimer

Toxicity: Standard Handling (A)

General description

Aminoglycoside related to gentamycin. Widely used in the selection of eukaryotic expression vectors. Toxic to both prokaryotic and eukaryotic cells. Liquid formulation of Cat. No. 345810.
Sterile-filtered solution of Cat. No. 345810.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Geneticin is a registered trademark of Gibco BRL Life Technologies, Inc.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nature communications, 14(1), 8227-8227 (2023-12-13)
Centromeres are epigenetically defined via the presence of the histone H3 variant CENP-A. Contacting CENP-A nucleosomes, the constitutive centromere associated network (CCAN) and the kinetochore assemble, connecting the centromere to spindle microtubules during cell division. The DNA-binding centromeric protein CENP-B
Rega H Kasim et al.
Frontiers in medical technology, 6, 1407409-1407409 (2024-07-29)
Ghrelin is an orexigenic peptide that becomes post-translationally modified. Natural autoantibodies to ghrelin (ghrelin-aAb) have been described in healthy subjects, in eating disorders and rheumatic diseases, with potential clinical relevance. Despite these important reports, the data base on the prevalence
Shunsuke Kawasaki et al.
Nature communications, 14(1), 2243-2243 (2023-04-20)
Translational modulation based on RNA-binding proteins can be used to construct artificial gene circuits, but RNA-binding proteins capable of regulating translation efficiently and orthogonally remain scarce. Here we report CARTRIDGE (Cas-Responsive Translational Regulation Integratable into Diverse Gene control) to repurpose
Yu Kaku et al.
Cell reports, 36(2), 109385-109385 (2021-07-09)
Administration of convalescent plasma or neutralizing monoclonal antibodies (mAbs) is a potent therapeutic option for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, SARS-CoV-2 variants with mutations in the spike protein have emerged
Mahya Eslami et al.
Frontiers in cell and developmental biology, 8, 577662-577662 (2020-11-27)
B cell activation factor of the TNF family (BAFF/BLyS), an essential B cell survival factor of which circulating levels are elevated in several autoimmune disorders, is targeted in the clinic for the treatment of systemic lupus erythematosus (SLE). The soluble
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