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341215

Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem

Shown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2.

Synonym(s):

Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem

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About This Item

CAS Number:
91262-95-2
UNSPSC Code:
12352200
MDL number:
MFCD00132134

Key Documents

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Product Name

Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem, Shown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2.

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

do not freeze

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Analysis Note

Single band by SDS-PAGE; single precipitin band by immunodiffusion

Biochem/physiol Actions

Cell permeable: no
Primary Target
ADP-ribosylation of elongation factor 2
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Highly Toxic (H)

General description

Shown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin, however it has distinct target-cell specificities and is immunologically unrelated.
Shown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin; however, it has distinct target-cell specificity and is immunologically unrelated.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Prentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.

Physical form

Solid lyophilized from 150 mM NaCl, 10 mM sodium phosphate buffer, pH 7.5.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Certificates of Analysis (COA)

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