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203410

BLEOCIN Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem

sterile; sterile-filtered, liquid

Synonym(s):

BLEOCIN Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem

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About This Item

Empirical Formula (Hill Notation):
C57H89CuN19O21S2 · 3HCl
CAS Number:
55658-47-4
Molecular Weight:
1613.49
UNSPSC Code:
12352200

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Product Name

BLEOCIN Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem, sterile; sterile-filtered, liquid

InChI key

NRVKJXFKQWUKCB-UHFFFAOYSA-N

InChI

1S/C57H89N19O21S2.ClH/c1-22-35(73-48(76-46(22)61)27(14-33(60)80)68-15-26(59)47(62)86)52(90)75-37(43(28-16-65-21-69-28)95-56-45(41(84)39(82)31(17-77)94-56)96-55-42(85)44(97-57(63)92)40(83)32(18-78)93-55)53(91)70-24(3)38(81)23(2)49(87)74-36(25(4)79)51(89)67-13-8-34-71-30(20-98-34)54-72-29(19-99-54)50(88)66-12-7-11-64-10-6-5-9-58;/h16,19-21,23-27,31-32,36-45,55-56,64,68,77-79,81-85H,5-15,17-18,58-59H2,1-4H3,(H2,60,80)(H2,62,86)(H2,63,92)(H,65,69)(H,66,88)(H,67,89)(H,70,91)(H,74,87)(H,75,90)(H2,61,73,76);1H

sterility

sterile; sterile-filtered

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

General description

A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells.
A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.
A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.

Other Notes

Sergeev, D.S., et al. 1995. Bioorg. Khim.21, 695.
Mulsant, P., et al. 1988. Somat. Cell Mol. Genet.14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry26, 931.
Takita, T., et al. 1972. J. Antibiot.25, 755.

Physical form

Sterile-filtered solution supplied at 20 mg/ml in H₂O.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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