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662091 Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GST-Ubc5a (E2)

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662091
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Recombinant, human ubiquitin conjugating enzyme 5a fused to GST and expressed in E. coli. E2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family which has been shown to play many important regulatory roles in inflammation and cancer.
      Catalogue Number662091
      Brand Family Calbiochem®
      SynonymsGST-Ubc5a (E2)
      References
      ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
      Ciechanover, A. 1994. Cell 79, 13.
      Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
      Product Information
      FormLiquid
      FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      662091 0

      Documentation

      Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      662091

      References

      Reference overview
      Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
      Ciechanover, A. 1994. Cell 79, 13.
      Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.

      Citations

      Title
    • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-September-2008 RFH
      SynonymsGST-Ubc5a (E2)
      DescriptionE2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family that has been shown to play many important regulatory roles in inflammation and cancer.
      FormLiquid
      FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
      Ciechanover, A. 1994. Cell 79, 13.
      Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
      Citation
    • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.
      		•