Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
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48-602MAG
Buffer Detection Kit for Magnetic Beads
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Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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559400
Sigma-AldrichSB 203580, Iodo- - CAS 189319-35-5 - Calbiochem
A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase.
More>>A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. Exhibits similar inhibitory potency as its parent compound SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites in p38 MAP kinase.
Catalogue Number
559400
Brand Family
Calbiochem®
Synonyms
4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
References
References
Tong, L., et al. 1997. Nat. Struct. Biol.4, 311.
Product Information
CAS number
189319-35-5
ATP Competitive
Y
Form
Off-white solid
Hill Formula
C₂₁H₁₆IN₃OS
Chemical formula
C₂₁H₁₆IN₃OS
Reversible
Y
Structure formula Image
Applications
Biological Information
Primary Target
p38 MAP kinase
Purity
≥95% by HPLC
Physicochemical Information
Cell permeable
Y
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Standard Handling
Storage
-20°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number
GTIN
559400
0
Documentation
SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem Certificates of Analysis
Title
Lot Number
559400
References
Reference overview
Tong, L., et al. 1997. Nat. Struct. Biol.4, 311.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
19-April-2011 RFH
Synonyms
4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
Description
A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase, similar to SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites of the p38 MAP kinase enzyme.
Form
Off-white solid
CAS number
189319-35-5
Chemical formula
C₂₁H₁₆IN₃OS
Structure formula
Purity
≥95% by HPLC
Solubility
DMSO (5 mg/ml)
Storage
Protect from light -20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
