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472804 S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
209589-59-3C₇H₁₅N₃O₂S · 2HCl

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472804-10MG
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      Description
      OverviewA cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
      Catalogue Number472804
      Brand Family Calbiochem®
      SynonymsNδ-(S-Methyl)isothioureido-L-ornithine
      References
      ReferencesKrishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
      Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
      Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.
      Product Information
      CAS number209589-59-3
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₇H₁₅N₃O₂S · 2HCl
      Chemical formulaC₇H₁₅N₃O₂S · 2HCl
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetRat neuronal nitric oxide synthase
      Primary Target IC<sub>50</sub>300 nM for rat neuronal nitric oxide synthase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      472804-10MG 04055977185331