472804 Sigma-AldrichS-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM).
More>> A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM). Less<<Synonyms: Nδ-(S-Methyl)isothioureido-L-ornithine
Recommended Products
Overview
Replacement Information |
---|
Key Spec Table
CAS # | Empirical Formula |
---|---|
209589-59-3 | C₇H₁₅N₃O₂S · 2HCl |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
---|---|---|---|---|---|---|
472804-10MG |
|
Plastic ampoule | 10 mg |
|
— |
References | |
---|---|
References | Krishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103. Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677. Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885. |
Product Information | |
---|---|
CAS number | 209589-59-3 |
ATP Competitive | N |
Form | White to off-white solid |
Hill Formula | C₇H₁₅N₃O₂S · 2HCl |
Chemical formula | C₇H₁₅N₃O₂S · 2HCl |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
---|
Biological Information | |
---|---|
Primary Target | Rat neuronal nitric oxide synthase |
Primary Target IC<sub>50</sub> | 300 nM for rat neuronal nitric oxide synthase |
Purity | ≥95% by HPLC |
Physicochemical Information | |
---|---|
Cell permeable | Y |
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS |
---|
Safety Information |
---|
Product Usage Statements |
---|
Storage and Shipping Information | |
---|---|
Ship Code | Ambient Temperature Only |
Toxicity | Standard Handling |
Storage | +2°C to +8°C |
Hygroscopic | Hygroscopic |
Do not freeze | Ok to freeze |
Packaging Information | |
---|---|
Packaged under inert gas | Packaged under inert gas |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
Catalogue Number | GTIN |
472804-10MG | 04055977185331 |
Documentation
S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem Certificates of Analysis
Title | Lot Number |
---|---|
472804 |
References
Reference overview |
---|
Krishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103. Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677. Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885. |