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524737 Phosphodiesterase 4C2, His•Tag®, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PDE4C2, cAMP-Specific Phosphodiesterase 4C2

524737
  
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      Overview

      Description
      Overview

      This product has been discontinued.





      Full-length, recombinant, human phosphodiesterdase 4C2 (accession no. U88712) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified preparation of the catalytically active enzyme.
      Catalogue Number524737
      Brand Family Calbiochem®
      SynonymsPDE4C2, cAMP-Specific Phosphodiesterase 4C2
      Application Data
      Phosphodiesterase 4C2 was treated with increasing concentration of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 7.87 µM.
      References
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Sullivan, M., et al. 1999. Cell Signal. 11, 735.
      Engels, P., et al. 1995. FEBS Lett. 358, 305.
      Product Information
      Activity≥ 0.5 units/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-HCl, 0.1% NP-40, pH 8.3.
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      524737 0