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165350 PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem

The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-Aminobenzamide

Primary Target: PARP
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165350
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
3544-24-9C₇H₈N₂O

Pricing & Availability

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165350-100MG
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      		 Plastic ampoule 100 mg
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      Description
      OverviewA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
      Catalogue Number165350
      Brand Family Calbiochem®
      Synonyms3-Aminobenzamide
      References
      ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
      Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
      Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
      Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
      Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.
      Product Information
      CAS number3544-24-9
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₇H₈N₂O
      Chemical formulaC₇H₈N₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPARP
      Purity≥99% by GC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSCU8992000
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      165350-100MG 04055977207675

      Documentation

      PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      165350

      References

      Reference overview
      Tiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
      Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
      Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
      Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
      Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-May-2014 JSW
      Synonyms3-Aminobenzamide
      DescriptionA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
      FormWhite solid
      CAS number3544-24-9
      RTECSCU8992000
      Chemical formulaC₇H₈N₂O
      Structure formulaStructure formula
      Purity≥99% by GC
      SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml), or H₂O (1 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
      Toxicity Irritant
      ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
      Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
      Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
      Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
      Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.