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492029 NRG1-β1/HRG1-β1 EGF Domain, Human, Recombinant

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492029
  
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      Overview

      Key Spec Table

      Purity
      ≥97% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, human neuregulin 1-β1/heregulin 1-β1 epidermal growth factor-like domain (NRG1-β1/HRG1-β1 EGF Domain), consisting of amino acids 176-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain that is required for binding directly to the ErbB3 or ErbB4 receptor tyrosine kinases.
      Catalogue Number492029
      Brand Family Calbiochem®
      References
      ReferencesBuonanno, A., and Fischbach, G.D. 2001. Curr. Opin. Neurobiol. 11, 287.
      Adlkofer, K. and Lai, C. 2000. Glia 29, 104.
      Garratt, A.N. et al. 2000. BioEssays 22, 987.
      Karey, K.P., et al. 1988. Cancer Res. 48, 4083.
      Product Information
      FormLyophilized
      FormulationLyophilized from 0.2 µm filtered acetonitrile, TFA, BSA.
      Quality LevelMQ100
      Biological Information
      Biological activityED₅₀ = 0.06-0.3 ng/ml as measured in a serum-free proliferation assay using MCF-7 human breast adenocarcinoma cells.
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1.0 EU/µg protein
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      492029 0