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EZML-82BK Mouse Leptin ELISA- Space Saver (Bulk) Packaging

This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: ELISA Detection Methods: Fluorescent, Colorimetric Research Category: Metabolism Research Sub-Category: Obesity, Metabolic Disorders
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EZML-82BK
96-well strip plate  
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      Overview

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Leptin MELISAFluorescent Colorimetric
      Description
      Catalogue NumberEZML-82BK
      DescriptionMouse Leptin ELISA- Space Saver (Bulk) Packaging
      Background InformationLeptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.
      Product Information
      Detection methodFluorescent Colorimetric
      Precision, %
      • Inter-assay: 3.0–4.6
      • Intra-assay: 1.1–1.8
      Quality LevelMQ200
      Applications
      ApplicationThis Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • ELISA
      Application NotesRoom temperature, 4 hour assay 10 µL sample size
      Biological Information
      Species Reactivity
      • Mouse
      Analytes Available
      • Leptin
      Entrez Gene SummaryThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
      SIZE: 167 amino acids; 18641 Da
      SUBUNIT: Interacts with SIGLEC6.
      SUBCELLULAR LOCATION: Secreted.
      DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
      SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
      Accuracy
      • 87–100%
      Physicochemical Information
      Sensitivity
      • 0.05 ng/mL
      Linearity of Dilution100–111%
      Standard Curve Range
      • 0.2–30 ng/mL
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Packaging Information
      Material Size96-well strip plate
      Global Trade Item Number
      Catalogue Number GTIN
      EZML-82BK 04053252437038