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444300 Melatonin - CAS 73-31-4 - Calbiochem

A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.

Melatonin - CAS 73-31-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine

Primary Target: rat NOS
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444300
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
73-31-4C₁₃H₁₆N₂O₂

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      Description
      OverviewA hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals. Counteracts the apoptotic effects of etoposide in bone marrow cells. Melatonin receptors are coupled to a G-protein system. Exhibits antioxidant properties. Has neuroprotective effects against Aβ peptides. Inhibits rat cerebellar nitric oxide synthase (NOS). Also acts as a peroxynitrite scavenger.
      Catalogue Number444300
      Brand Family Calbiochem®
      SynonymsN-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine
      References
      ReferencesPappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
      Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
      Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
      Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
      Pozo, D., et al. 1994. Life Sciences 55, PL455.
      Product Information
      CAS number73-31-4
      ATP CompetitiveN
      FormWhite to slightly yellow powder
      Hill FormulaC₁₃H₁₆N₂O₂
      Chemical formulaC₁₃H₁₆N₂O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetrat NOS
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSAC5955000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      444300-1GM 04055977186123

      Documentation

      Melatonin - CAS 73-31-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Melatonin - CAS 73-31-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      444300

      References

      Reference overview
      Pappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
      Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
      Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
      Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
      Pozo, D., et al. 1994. Life Sciences 55, PL455.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-February-2018 JSW
      SynonymsN-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine
      DescriptionA hormone that has been postulated as being a mediator of photic-induced anti-gonadotropic activity in photoperiodic mammals. Counteracts the apoptotic effects of etoposide in bone marrow cells. Melatonin receptors are coupled to a G-protein system. Inhibits rat cerebellar nitric oxide synthase (NOS).
      FormWhite to slightly yellow powder
      CAS number73-31-4
      RTECSAC5955000
      Chemical formulaC₁₃H₁₆N₂O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityMethanol (50 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 5816
      ReferencesPappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
      Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
      Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
      Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
      Pozo, D., et al. 1994. Life Sciences 55, PL455.