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401250 Ilimaquinone - CAS 71678-03-0 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
71678-03-0C₂₂H₃₀O₄

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401250-100UG
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      Plastic ampoule 100 μg
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      Description
      OverviewA cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules. Inhibits cellular methylations through its interaction with S-adenosylhomocysteinase. Blocks the cytotoxicity of ricin and diphtheria toxin. Acts as an inhibitor of the RNase H activity of HIV-1.
      Catalogue Number401250
      Brand Family Calbiochem®
      Synonyms3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-napthyl)methyl]-2-hydroxy-5-methoxybenzoquinone, IQ
      References
      ReferencesRadeke, H.S., et al. 1999. Chem. Biol. 6, 639.
      Radeke, H.S., and Snapper, M.L. 1998. Bioorg. Med. Chem. 6, 1227.
      Jamora, C., et al. 1997. Cell 91, 617.
      Nambiar, M.P., and Wu, H.C. 1995. Exp. Cell Res. 219, 671.
      Loya, S., and Hizi, A. 1993. J. Biol. Chem. 268, 9323.
      Takizawa, P.A., et al. 1993. Cell 73, 1079.
      Veit, B., et al. 1993. J. Cell Biol. 122, 1197.
      Product Information
      CAS number71678-03-0
      ATP CompetitiveN
      FormRed solid
      Hill FormulaC₂₂H₃₀O₄
      Chemical formulaC₂₂H₃₀O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetInduces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules.
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      401250-100UG 04055977188943