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401483 IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (5-Phenyl-2-ureido)thiophene-3-carboxamide

Primary Target: IKK-2
401483
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      354811-10-2C₁₂H₁₁N₃O₂S
      Description
      Overview

      This product has been discontinued.



      An ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
      Catalogue Number401483
      Brand Family Calbiochem®
      Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
      References
      ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
      Product Information
      CAS number354811-10-2
      ATP CompetitiveY
      FormOff-white solid
      Hill FormulaC₁₂H₁₁N₃O₂S
      Chemical formulaC₁₂H₁₁N₃O₂S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetIKK-2
      Primary Target IC<sub>50</sub>13 nM
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      401483 0

      Documentation

      IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      401483

      References

      Reference overview
      Baxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-April-2011 RFH
      Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
      DescriptionAn ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number354811-10-2
      Chemical formulaC₁₂H₁₁N₃O₂S
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.