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GF306 IGF-I Protein, Human Recombinant Animal Free

The Insulin-like growth factor I protein(or IGF-1 protein), also known as somatomedin C, is the dominant effector of growth hormone & is structurally homologous to proinsulin. Manufactured using all non-animal reagents.

IGF-I Protein, Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P05019 Entrez Gene Number: NM_000618.2
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GF306
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF306
      DescriptionIGF-I Protein, Human Recombinant Animal Free
      Alternate Names
      • IGF-1
      • IGF1
      • Insulinlike Growth Factor I
      • Insulinlike Growth Factor 1
      • Mechano growth factor
      • Somatomedin-C
      • IGFI
      Background InformationInsulinlike growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.
      References
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationThe Insulin-like growth factor I protein(or IGF-1 protein), also known as somatomedin C, is the dominant effector of growth hormone & is structurally homologous to proinsulin. Manufactured using all non-animal reagents.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityMouse, Rat, Horse, Pig, Cow, Sheep, Monkey, Chicken, Tiger Salamander, Bacteria, Frog
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF306 04053252691287

      Documentation

      IGF-I Protein, Human Recombinant Animal Free SDS

      Title

      Safety Data Sheet (SDS) 

      IGF-I Protein, Human Recombinant Animal Free Certificates of Analysis

      TitleLot Number
      Recombinant Animal Free Human IGF-I - 2137050 2137050
      Recombinant Animal Free Human IGF-I Recombinant Protein - 2421766 2421766
      Recombinant Animal Free Human IGF-I Recombinant Protein - 2433593 2433593
      Recombinant Animal Free -2659615 2659615
      Recombinant Animal Free -2668530 2668530
      Recombinant Animal Free -2676708 2676708
      Recombinant Animal Free -2708971 2708971
      Recombinant Animal Free -2718255 2718255
      Recombinant Animal Free -2722975 2722975
      Recombinant Animal Free -2766520 2766520
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