218729 Sigma-AldrichCaspase Inhibitor VIII
The Caspase Inhibitor VIII controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
More>> The Caspase Inhibitor VIII controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications. Less<<Caspase Inhibitor VIII MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Ac-VDVAD-CHO
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Overview
Key Spec Table
| Empirical Formula |
|---|
| C₂₃H₃₇N₅O₁₀ |
| References | |
|---|---|
| References | Dorstyn, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4307. Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Off-white lyophilized solid |
| Hill Formula | C₂₃H₃₇N₅O₁₀ |
| Chemical formula | C₂₃H₃₇N₅O₁₀ |
| Reversible | Y |
| Biological Information | |
|---|---|
| Primary Target | caspase-2 |
| Primary Target K<sub>i</sub> | 3.5 nM, 1 nM, 7.5 nM, against caspase-2, caspase-3. and caspase-7, respectively |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | Ac-Val-Asp-Val-Ala-Asp-CHO |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 218729 | 0 |