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217460 Cardiogenol C - CAS 671225-39-1 - Calbiochem

Cardiogenol C - CAS 671225-39-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine

Primary Target: Differentiation of ESCs (embryonic stem cells) into cardiomyocytes
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      671225-39-1C₁₃H₁₆N₄O₂
      Description
      Overview

      This product has been discontinued.



      A cell-permeable pyrimidine compound that potently induces the differentiation of ESCs (embryonic stem cells) into cardiomyocytes (EC50 = 100 nM) without significant cytotoxic effect even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is much more efficient than that achieved by EBs (embryoid bodies) formation and DMSO treatment.
      Catalogue Number217460
      Brand Family Calbiochem®
      Synonyms2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine
      References
      ReferencesWu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.
      Product Information
      CAS number671225-39-1
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₃H₁₆N₄O₂
      Chemical formulaC₁₃H₁₆N₄O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetDifferentiation of ESCs (embryonic stem cells) into cardiomyocytes
      Primary Target IC<sub>50</sub>EC50 = 100 nM inducing the differentiation of ESCs (embryonic stem cells) into cardiomyocytes
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      217460 0

      Documentation

      Cardiogenol C - CAS 671225-39-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cardiogenol C - CAS 671225-39-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      217460

      References

      Reference overview
      Wu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      Synonyms2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine
      DescriptionA cell-permeable pyrimidine compound that potently induces the differentiation of embryonic stem cells (ESCs) into cardiomyocytes (EC50 = 100 nM). Does not exhibit cytotoxic effects even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is reported to be more efficient than that achieved by embryoid bodies (EBs) and DMSO treatment.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number671225-39-1
      Chemical formulaC₁₃H₁₆N₄O₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Carcinogenic / Teratogenic
      ReferencesWu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.