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196419 BAPTA/AM - CAS 126150-97-8 - Calbiochem

BAPTA/AM - CAS 126150-97-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester

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196419
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Overview

Key Spec Table

CAS #Empirical Formula
126150-97-8C₃₄H₄₀N₂O₁₈

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196419-25MG
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      Description
      OverviewMembrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D3-induced increase in intracellular Ca2+. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.
      Catalogue Number196419
      Brand Family Calbiochem®
      Synonyms1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester
      References
      ReferencesBissonnette, M., et al. 1994. Am. J. Physiol. 267, G465.
      Jiang, S., et al. 1994. Exp. Cell Res. 212, 84.
      Billman, G.E. 1993. Am. J. Physiol. 265, H1529.
      Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171.
      Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133.
      Harrison, S.M., and Bers, D.M. 1987. J. Biophys. 51, 102A.
      Marban, E., et al. 1986. J. Clin. Invest. 78, 1185.
      Tsien, R.Y. 1981. Nature 290, 527.
      Tsien, R.Y. 1980. Biochemistry 19, 2396.
      Product Information
      CAS number126150-97-8
      FormLight yellow solid
      Hill FormulaC₃₄H₄₀N₂O₁₈
      Chemical formulaC₃₄H₄₀N₂O₁₈
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥90% by TLC
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, purge with inert gas and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      196419-25MG 04055977206494