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07-502-I Anti-p67-phox (not Human) Antibody

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07-502-I
100 μg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number07-502-I
      DescriptionAnti-p67-phox (not Human) Antibody
      Alternate Names
      • Neutrophil cytosol factor 2
      • NCF-2
      • 67 kDa neutrophil oxidase factor
      • NADPH oxidase activator 2
      • Neutrophil NADPH oxidase factor 2
      • p67-phox
      • p67-phox (rodent)
      Background InformationNeutrophil cytosol factor 2 (UniProt Q09014; also known as 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, NADPH oxidase subunit 67 kDa, NCF-2, Ncf2, Neutrophil NADPH oxidase factor 2, p67-phox, p47phox) is encoded by the murine Ncf2 (also known as Noxa2, p67phox) gene in murine species (Gene ID 17970). Activation of NADPH-oxidase dependent superoxide generation requires the participation of several cytosolic factors, including p47-phox, p67-phox, p40-phox and Rac. In the resting cell p47phox, p67phox, and p40phox form a large molecular weight cytosolic complex. Activation of the NADPH oxidase is initiated by the assembly of p47phox, p67phox, and Rac with cytochrome b558 in a 1:1:1:1 complex in the plasma membrane.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-p67-phox (not Human) Antibody is an antibody against p67-phox, tested in mouse and rat, but is not expected to react with human, for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected p67-phox (rodent) in rat colon and mouse hindbrain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of mouse p67-phox.
      EpitopeN-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Ncf2
      • Noxa2
      • P67phox
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~72 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in C6 and THP-1 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected p67-phox (rodent) in 10 µg of C6 and THP-1 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      07-502-I 04055977170658