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565953 Anti-Sialyl Lewis x Mouse mAb (KM93)

This Anti-Sialyl Lewis x Mouse mAb (KM93) is validated for use in Flow Cytometry, Adhesion Blockade, Paraffin Sections for the detection of Sialyl Lewis x.

Anti-Sialyl Lewis x Mouse mAb (KM93) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Sialyl Lex

565953
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      M
      Description
      Overview

      This product has been discontinued.





      Recognizes the SLex carbohydrate epitope on glycoproteins and glycolipids on adenocarcinomas in lung primary tumors and with a variety of tumor cell lines.
      Catalogue Number565953
      Brand Family Calbiochem®
      SynonymsAnti-Sialyl Lex
      References
      ReferencesNagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
      Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.
      Product Information
      FormLiquid
      FormulationIn PBS, 1% BSA, pH 7.2.
      Preservative≤0.1% sodium azide
      Applications
      Data setup Error. Pagelet <collection_feature_application_id-AB> not found.
      Flow Cytometry
      Paraffin Sections
      Application NotesFlow Cytometry (10 µg/ml)
      Adhesion Blockade (10-100 µg/ml)
      Paraffin Sections (1:40)
      Application CommentsReacts with various cancerous tissue, including adenocarcinomas, cholangioma, and cancers of the stomach, colon, pancreas, breast, cervix, ovary mucinic cystic gland, and squamous cell epithelia. Reacts with various normal adult tissues, including stomach, colon, bronchus, pancreatic acinar cells, germ cells, some myeloid cells, and epithelia of the lung, pancreatic duct, gall duct, and renal tubule. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenhuman lung adenocarcinoma cells
      ImmunogenHuman
      CloneKM93
      HostMouse
      IsotypeIgM
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      565953 0

      Documentation

      Anti-Sialyl Lewis x Mouse mAb (KM93) Certificates of Analysis

      TitleLot Number
      565953

      References

      Reference overview
      Nagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
      Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-August-2007 RFH
      SynonymsAnti-Sialyl Lex
      ApplicationFlow Cytometry (10 µg/ml)
      Adhesion Blockade (10-100 µg/ml)
      Paraffin Sections (1:40)
      DescriptionPurified mouse monoclonal antibody. Recognizes the Sialyl Lewis x epitope on glycoproteins and glycolipids.
      BackgroundSialyl Lewis x [SLex; NeuAcα2,3Galβ1,4(Fucα1,3)GlcNAc] is a tetrasaccharide that acts as a minimal ligand (Kd = 129 µM) for E-selectin (ELAM; endothelial leukocyte adhesion molecule), an endothelial cell-surface glycoprotein that mediates recruitment of neutrophils and monocytes to sites of endothelial inflammation.
      HostMouse
      Immunogen speciesHuman
      Immunogenhuman lung adenocarcinoma cells
      CloneKM93
      IsotypeIgM
      Specieshuman
      FormLiquid
      FormulationIn PBS, 1% BSA, pH 7.2.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsReacts with various cancerous tissue, including adenocarcinomas, cholangioma, and cancers of the stomach, colon, pancreas, breast, cervix, ovary mucinic cystic gland, and squamous cell epithelia. Reacts with various normal adult tissues, including stomach, colon, bronchus, pancreatic acinar cells, germ cells, some myeloid cells, and epithelia of the lung, pancreatic duct, gall duct, and renal tubule. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesNagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
      Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies