Millipore Sigma Vibrant Logo

MABF804 Anti-CD11b, (human/mouse), redFluor™ 710 Antibody, clone M1/70

This rat monoclonal Anti-CD11b Antibody, (human/mouse), redFluor™ 710, clone M1/70, Cat. No. MABF804 is validated for use in Flow Cytometry, for the detection of CD11b.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Itgam UniProt Number: P05555
View Products on Sigmaaldrich.com
MABF804
100 μg  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Special Offers

      100% Performance Guaranteed

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MFCRredFluor™ 710Monoclonal Antibody
      Description
      Catalogue NumberMABF804
      DescriptionAnti-CD11b, (human/mouse), redFluor™ 710 Antibody, clone M1/70
      Alternate Names
      • Integrin alpha-M
      • CD11 antigen-like family member B
      • CR-3 alpha chain
      • Cell surface glycoprotein MAC-1 subunit alpha
      • Leukocyte adhesion receptor MO1
      • CD11b
      • CD11b
      Background InformationThe M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.
      References
      Product Information
      FormatredFluor™ 710
      PresentationPurified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationThis rat monoclonal Anti-CD11b Antibody, (human/mouse), redFluor™ 710, clone M1/70, Cat. No. MABF804 is validated for use in Flow Cytometry, for the detection of CD11b.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      CloneM1/70
      ConcentrationPlease refer to lot specific datasheet.
      HostRat
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Itgam
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.25 μg from a representative lot detected CD11b in one million C57Bl/6 bone marrow cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF804 04055977291049

      Related Products & Applications

      Related Products

      Catalogue Number Description  
      MABF800 Anti-CD11b, (human/mouse), FITC, clone M1/70 Antibody Show Pricing & Availability
      MABF801 Anti-CD11b, (human/mouse), FITC, clone M1/70 Antibody Show Pricing & Availability
      MABF802 Anti-CD11b, (human/mouse), FITC, clone M1/70 Antibody Show Pricing & Availability
      MABF803 Anti-CD11b, (human/mouse), redFluor™ 710, clone M1/70 Antibody Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies