101500 Sigma-AldrichAEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem
AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP.
More>> AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
Recommended Products
Overview
| Replacement Information |
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 30827-99-7 | C₈H₁₀FNO₂S · HCl |
Pricing & Availability
| Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
|---|---|---|---|---|---|---|
| 101500-100MG |
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Glass bottle | 100 mg |
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| 101500-1GM |
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Glass bottle | 1 gm |
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| 101500-500MG |
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Plastic ampoule | 500 mg |
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| 101500-50MG |
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Glass bottle | 50 mg |
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| Description | |
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| Overview | Specific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H2O (Cat. No. 508436). |
| Catalogue Number | 101500 |
| Brand Family | Calbiochem® |
| Synonyms | 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl |
| Application Data |  |
| Product Information | |
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| CAS number | 30827-99-7 |
| ATP Competitive | N |
| Form | White to off-white solid |
| Hill Formula | C₈H₁₀FNO₂S · HCl |
| Chemical formula | C₈H₁₀FNO₂S · HCl |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | chymotrypsin |
| Purity | >97% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 101500-100MG | 04055977226317 |
| 101500-1GM | 04055977226300 |
| 101500-500MG | 04055977226348 |
| 101500-50MG | 04055977226331 |
Documentation
AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem SDS
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AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 101500 |
References
| Reference overview |
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| Citron, M., et al. 1996. Neuron 17, 171. Ohkubo, I., et al. 1994. J. Biochem. 116, 1182. Mintz, G.R. 1993. BioPharm. 6, 34. Lawson, W.B., et al. 1982. Folia Haematol. 109, 52. Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247. Markwardt, F., et al. 1973. Thromb. Res. 2, 343. Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119. |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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