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539154 20S Proteasome, Rabbit

20S Proteasome is a catalytic core enzyme of the 26S proteasome that degrades ubiquitinated proteins. Fully functional with Z-LLVY-AMC as the substrate.

20S Proteasome, Rabbit MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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539154
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Native, rabbit 20S proteasome. Catalytic core enzyme of the 26S proteasome that degrades ubiquitinated proteins. Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP-dependent process. Can be activated by PA28 (Cat. No. 506280) or SDS.
      Catalogue Number539154
      Brand Family Calbiochem®
      References
      ReferencesStein, R.L., et al. 1996. Biochemistry 35, 3899.
      Ciechanover, A. 1994. Cell 79, 13.
      Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
      Dick, L.R., et al. 1991. Biochemistry 30, 2725.
      Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.
      Product Information
      FormLiquid
      FormulationIn 150 mM NaCl, 50 mM HEPES, 1 mM DTT, pH 7.6.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityFully functional as measured using Z-LLVY-AMC as the substrate following SDS activation
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      539154 0

      Documentation

      20S Proteasome, Rabbit SDS

      Title

      Safety Data Sheet (SDS) 

      20S Proteasome, Rabbit Certificates of Analysis

      TitleLot Number
      539154

      References

      Reference overview
      Stein, R.L., et al. 1996. Biochemistry 35, 3899.
      Ciechanover, A. 1994. Cell 79, 13.
      Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
      Dick, L.R., et al. 1991. Biochemistry 30, 2725.
      Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.

      Brochure

      Title
      Proteasomes Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-September-2008 RFH
      DescriptionNative, rabbit 20S proteasome. Catalytic core of the 26S proteasome that degrades ubiquitinated proteins. Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP-dependent process. Can be activated by PA28 Activator (Cat. No. 506280) or SDS.
      FormLiquid
      FormulationIn 150 mM NaCl, 50 mM HEPES, 1 mM DTT, pH 7.6.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Biological activityFully functional as measured using Z-LLVY-AMC as the substrate following SDS activation
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesStein, R.L., et al. 1996. Biochemistry 35, 3899.
      Ciechanover, A. 1994. Cell 79, 13.
      Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
      Dick, L.R., et al. 1991. Biochemistry 30, 2725.
      Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.