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MABS676 Anti-KLF15, clone 2G8 Antibody

MABS676
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABS676
      DescriptionAnti-KLF15, clone 2G8 Antibody
      Alternate Names
      • Krueppel-like factor 15
      • Kidney-enriched krueppel-like factor
      • KLF15
      Background InformationKLF15 (Kruppel-like factor 15), also known as KKLF, DKFZp779M1320. Entrez Protein NP_054798. Sequence analysis predicted that the 416 amino acid KLF15 protein, which is 84% identical to the rat Klf15 protein, contains 3 zinc finger motifs at its C terminus, N-terminal serine-rich stretches, and a central proline-rich segment.KLF15, a kidney-enriched Krueppel-like factor, is a transcriptonal activator that binds the CLCNKA promoter. KLF15, which is a nuclear protein, is expressed primarily in liver, heart, skeletal muscle and kidney tissues but is not detected in lymphoid tissues or bone marrow. KLF15 is an important regulator of GLUT4 in both adipose and muscle tissues.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide. 
      Quality LevelMQ300
      Applications
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of human KLF15 expressed in E. Coli.
      Clone2G8
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • KLF15
      • KKLF
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~43 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2 and SMMC-7721 cell lysates.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected KLF15 in HepG2 and SMMC-7721 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS676 04055977172164

      Documentation

      Anti-KLF15, clone 2G8 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-KLF15, clone 2G8 Antibody Certificates of Analysis

      TitleLot Number
      Anti-KLF15, clone 2G8 - VP1902011 VP1902011
      Anti-KLF15, clone 2G8 -QVP1502046 QVP1502046
      Anti-KLF15, clone 2G8 -VP1609046 VP1609046
      Anti-KLF15, clone 2G8 Monoclonal Antibody VP1803232

      Technical Info

      Title
      Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
      White Paper: Further considerations of antibody validation and usage.