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MABN1594 Anti-WWOX Antibody, clone 12G5

Anti-WWOX Antibody, clone 12G5 | MABN1594 is an antibody against WWOX Antibody for use in Western Blotting, Immunohistochemistry.

Anti-WWOX Antibody, clone 12G5 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Wwox, Wox1
UniProt Number: Q91WL8
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MABN1594
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IHCRPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN1594
      DescriptionAnti-WWOX Antibody, clone 12G5
      Alternate Names
      • WW domain-containing oxidoreductase
      Background InformationWW domain-containing oxidoreductase (WWOX) is also called Fragile site FRA16D oxidoreductase (FOR). WWOX is a putative oxidoreductase that functions as a tumor suppressor and is involved in apoptosis. WWOX is also required for normal bone development, and inhibits Wnt signaling. WWOX is widely expressed, but is most strongly expressed in testis, prostate, and ovary as well as in cancer cell lines. Certain isoforms (Isoform 5 and isoform 6) are thought to only be expressed in tumor cell lines. WWOX is linked to several cancer types like Esophageal cancer (ESCR).
      References
      Product Information
      FormatPurified
      PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-WWOX Antibody, clone 12G5 | MABN1594 is an antibody against WWOX Antibody for use in Western Blotting, Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected WWOX in 10 µg of mouse 11 day embreyo and mouse E13-14 Brain tissue lysate.
      Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in human cerebellum and human cerebral cortex tissue.
      Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in mouse cerebellum and mouse hindbrain tissue.
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse WWOX.
      Clone12G5
      ConcentrationPlease refer to lot specific datasheet.
      HostRat
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Wwox
      • Wox1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~46 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected WWOX in 10 µg of HepG2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN1594 04055977125368