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MABN153 Anti-HuC/HuD Antibody, clone 15A7.1

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MABN153
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, MWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN153
      DescriptionAnti-HuC/HuD Antibody, clone 15A7.1
      Alternate Names
      • ELAV-like protein 3
      • Hu-antigen C
      • HuC
      • Paraneoplastic cerebellar degeneration-associated antigen
      • Paraneoplastic limbic encephalitis antigen 21
      • ELAV-like protein 4
      • Hu-antigen D
      • HuD
      • Paraneoplastic encephalomyelitis antigen HuD
      Background InformationHu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. RNA binding protein HuC promotes neuronal development in both the central and the peripheral nervous systems. HuC antibodies are used as markers for developing neurons. HuD may play a role in neuron-specific RNA processing, and be involved in maintaining the proliferative state of cells.
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      Control
      • Human brain tissue lysate
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis HuC/HuD antibody is validated for use in WB & IHC for the detection of the HuC/HuD protein.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected HuC/HuD in human brain and rat hippocampus tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human HuC/HuD.
      Clone15A7.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ELAVL3
      • HUC
      • PLE21
      • ELAVL4
      • HUD
      • PNEM
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 40 kDa observed. An uncharacterized band may appear at ~45 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human brain tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected HuC/HuD in 200 µg of human brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN153 04053252858307

      Documentation

      Anti-HuC/HuD Antibody, clone 15A7.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-HuC/HuD Antibody, clone 15A7.1 Certificates of Analysis

      TitleLot Number
      Anti-HuC/HuD, clone 15A7.1 - 3192033 3192033
      Anti-HuC/HuD, clone 15A7.1 - 3328969 3328969
      Anti-HuC/HuD, clone 15A7.1 - 3494039 3494039
      Anti-HuC/HuD, clone 15A7.1 - 3776222 3776222
      Anti-HuC/HuD, clone 15A7.1 - 3931723 3931723
      Anti-HuC/HuD, clone 15A7.1 - 4138120 4138120
      Anti-HuC/HuD, clone 15A7.1 - 4206950 4206950
      Anti-HuC/HuD, clone 15A7.1 - Q2139711 Q2139711
      Anti-HuC/HuD, clone 15A7.1 -2520567 2520567
      Anti-HuC/HuD, clone 15A7.1 -2573009 2573009