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MABN139 Anti-mGluR5 Antibody, clone 11D9.1

Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.

Anti-mGluR5 Antibody, clone 11D9.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: GRM5, GPRC1E, MGLUR5 UniProt Number: P41594
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MABN139
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN139
      DescriptionAnti-mGluR5 Antibody, clone 11D9.1
      Alternate Names
      • Metabotropic glutamate receptor 5
      • mGluR5
      Background InformationMetabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      Control
      • Rat brain micropreparation tissue lysate
      PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human mGluR5.
      Clone11D9.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2bκ
      Species Reactivity
      • Rat
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GRM5
      • GPRC1E
      • MGLUR5
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain micropreparation tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected mGluR5 in 10 µg of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN139 04053252880216

      Documentation

      Anti-mGluR5 Antibody, clone 11D9.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-mGluR5 Antibody, clone 11D9.1 Certificates of Analysis

      TitleLot Number
      Anti-mGluR5, clone 11D9.1 - 3236370 3236370
      Anti-mGluR5, clone 11D9.1 - 3525955 3525955
      Anti-mGluR5, clone 11D9.1 - 3899586 3899586
      Anti-mGluR5, clone 11D9.1 - 4176596 4176596
      Anti-mGluR5, clone 11D9.1 - Q2159801 Q2159801
      Anti-mGluR5, clone 11D9.1 -2548724 2548724
      Anti-mGluR5, clone 11D9.1 -2566788 2566788
      Anti-mGluR5, clone 11D9.1 -2887465 2887465
      Anti-mGluR5, clone 11D9.1 Monoclonal Antibody 2976875
      Anti-mGluR5, clone 11D9.1 Monoclonal Antibody 2903066

      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer