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MABE1020 Anti-Acetyl Lysine, Pan, clone RM101 Antibody

Anti-Acetyl Lysine, Pan, clone RM101 is an antibody against Acetyl Lysine, Pan for use in WB, Dot Blot, ICC, IP.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Nuclear Receptors
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MABE1020
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, DB, ICC, IPRbAffinity PurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABE1020
      DescriptionAnti-Acetyl Lysine, Pan, clone RM101 Antibody
      Background InformationDNA is tightly packed in the nucleus into nucleosomes, generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit monoclonal IgG in buffer containing PBS with 1% BSA and 0.09% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Acetyl Lysine, Pan, clone RM101 is an antibody against Acetyl Lysine, Pan for use in WB, Dot Blot, ICC, IP.
      Key Applications
      • Western Blotting
      • Dot Blot
      • Immunocytochemistry
      • Immunoprecipitation
      Application NotesImmunocytochemistry Analysis: A representative lot detected Acetyl Lysine, Pan in A431 cells.
      Dot Blot Analysis: A 1:2,000 dilution from a representative lot detected Acetyl Lysine, Pan in an Absurance™ Histone H3 Antibody Specificity Array (Cat. No. 16-667) and an Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array (Cat. No. 16-665).
      Immunoprecipitation Analysis: A 1:500 dilution from a representative lot immunoprecipitated Acetyl Lysine, Pan in A431 cell lysate.
      Biological Information
      ImmunogenAcetyl lysine-BSA corresponding to all species.
      CloneRM101
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with All based on 100% sequence homology.
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein A Purfied
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Trichostatin A (TSA) treated HeLa cell lysate.

      Western Blotting Analysis: A 1:2,000 of this antibody detected Acetyl Lysine, Pan in Trichostatin A (TSA) treated HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABE1020 04055977115833

      Documentation

      Anti-Acetyl Lysine, Pan, clone RM101 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Acetyl Lysine, Pan, clone RM101 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Acetyl Lysine, Pan, clone RM101 QVP1406133
      Anti-Acetyl Lysine, Pan, clone RM101 - VP1907260 VP1907260
      Anti-Acetyl Lysine, Pan, clone RM101 - VP2205196 VP2205196
      Anti-Acetyl Lysine, Pan, clone RM101 -VP1508081 VP1508081
      Anti-Acetyl Lysine, Pan, clone RM101 -VP1511215 VP1511215
      Anti-Acetyl Lysine, Pan, clone RM101 -VP1601282 VP1601282
      Anti-Acetyl Lysine, Pan, clone RM101 Monoclonal Antibody VP1806150
      Anti-Acetyl Lysine, Pan, clone RM101 Monoclonal Antibody VP1710204
      Anti-Acetyl Lysine, Pan, clone RM101 Monoclonal Antibody VP1808032