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DR1058 Anti-SOCS3 Mouse mAb (1E4)

This Anti-SOCS3 Mouse mAb (1E4) is validated for use in ELISA, Paraffin Sections for the detection of SOCS3.

Anti-SOCS3 Mouse mAb (1E4) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Suppressor Cytokine Signaling 3

DR1058
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      HMMonoclonal Antibody
      Description
      OverviewRecognizes the SOCS3 protein in human colon tissue.
      Catalogue NumberDR1058
      Brand Family Calbiochem®
      SynonymsAnti-Suppressor Cytokine Signaling 3
      Application Data
      Detection of human SOCS3 by staining paraffin sections. Sample: Formalin-fixed, paraffin embedded human colon tissue. Primary antibody: Anti-SOCS3 Mouse mAb (1E4) (Cat. No. DR1058) (1.5 µg/ml). Detection: colorimetric (DAB).
      References
      Product Information
      Formliquid
      FormulationIn PBS, pH 7.2.
      Positive controlHuman colon tissue
      PreservativeNone
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Paraffin Sections
      Application NotesELISA (see comments)
      Paraffin Sections (1.5 µg/ml)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      ImmunogenFull-length, recombinant human SOCS3 (aa 1-226), expressed as a GST fusion protein
      ImmunogenNA
      Clone1E4
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      DR1058 0

      Documentation

      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-November-2010 RFH
      SynonymsAnti-Suppressor Cytokine Signaling 3
      ApplicationELISA (see comments)
      Paraffin Sections (1.5 µg/ml)
      Application Data
      Detection of human SOCS3 by staining paraffin sections. Sample: Formalin-fixed, paraffin embedded human colon tissue. Primary antibody: Anti-SOCS3 Mouse mAb (1E4) (Cat. No. DR1058) (1.5 µg/ml). Detection: colorimetric (DAB).
      DescriptionPurified mouse monoclonal antibody. Recognizes the SOCS3 protein.
      BackgroundThis protein is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. This protein can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
      HostMouse
      Immunogen speciesNA
      ImmunogenFull-length, recombinant human SOCS3 (aa 1-226), expressed as a GST fusion protein
      Clone1E4
      IsotypeIgG2b
      Specieshuman
      Positive controlHuman colon tissue
      Formliquid
      FormulationIn PBS, pH 7.2.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review