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ABN343 Anti-NIPSNAP Antibody

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ABN343
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN343
      DescriptionAnti-NIPSNAP Antibody
      Alternate Names
      • Non-neuronal SNAP25-like protein
      • NIPSNAP1
      • NIPSNAP
      Background InformationNIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) brain, suggesting that NIPSNAP may play a role in memory.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the NIPSNAP protein using this Anti-NIPSNAP validated for use in WB & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected NIPSNAP in human brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human NIPSNAP.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • NIPSNAP1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~33 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human brain tissue lysate.

      Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN343 04053252847448