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ABC970 Anti-Syntaxin 17 Antibody

This Anti-Syntaxin 17 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of Syntaxin 17.

Anti-Syntaxin 17 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: STX17 UniProt Number: P56962
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ABC970
100 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC970
      DescriptionAnti-Syntaxin 17 Antibody
      Alternate Names
      • Syntaxin 17
      Background InformationSyntaxin-17 (UniProt P56962) is encoded by the STX17 gene (Gene ID 55014) in human. Syntaxin-17 belongs to the Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor (SNARE) family of proteins that mediate membrane fusion events. Syntaxin-17 functions as the autophagosomal Qa-SNARE required for autophagosome-lysosome fusion and it mediates the fusion process by binding to its partner SNAREs, synaptosomal-associated protein 29 (SNAP29; Qbc-SNARE), and vesicle-associated membrane protein 8 (VAMP8; R-SNARE). In addition, the homotypic fusion and protein sorting (HOPS) complex is reported to interact with Syntaxin-17 and promotes Syntaxin-17-dependent autophagosome-lysosome fusion.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Syntaxin 17 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of Syntaxin 17.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected Syntaxin 17 in human kidney and human adrenal gland tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Syntaxin 17.
      Epitopecytoplasmic domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Mouse, Bovine, Rhesus Macaque based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • STX17
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~38 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human adrenal tissue lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected Syntaxin 17 in 10 µg of human adrenal tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC970 04055977274806