Millipore Sigma Vibrant Logo

AB5681-I Anti-Somatostatin Receptor Type 5 Antibody

This Anti-Somatostatin Receptor Type 5 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of Somatostatin Receptor Type 5 .

Anti-Somatostatin Receptor Type 5 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: SSTR5 UniProt Number: P35346
AB5681-I
100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Special Offers

      100% Performance Guaranteed

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB5681-I
      ReplacesAB5681
      DescriptionAnti-Somatostatin Receptor Type 5 Antibody
      Alternate Names
      • Somatostatin receptor type 5
      • SS-5-R
      • SS5-R
      • SS5R
      Background InformationSomatostatin receptor type 5 (UniProt P35346; also known as SS-5-R, SS5-R, SS5R) is encoded by the SSTR5 gene (Gene ID 6755) in human. Somatostatin receptor type 5 is an inhibitory G-protein coupled receptor (GPCR) which regulates hormone secretion in the pituitary and in pancreatic islets. SSTR5 uses its PDZ ligand motif to interact with PSD-95/discs large/ZO-1 (PDZ) domain proteins, such as the Golgi-associated protein PIST (also termed GOPC, CAL or FIG), endosomal sorting nexin 27 (SNX27), and the scaffold proteins NHERF-1 & NHERF-3 (PDZ-K1). SNX27 is reported to stabilize SSTR5 by preventing its lysosomal degradation, while NHERF-1 & NHERF-3 mediate SSTR5 plasma membrane localizatin and enable its coupling to signaling partners, such as phospholipase C-β3. PIST stabilizes SSTR5 association with the trans-Golgi network (TGN) before it is recruited to the plasma membrane by NHERF proteins.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Somatostatin Receptor Type 5 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of Somatostatin Receptor Type 5 .
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Somatostatin Receptor Type 5 in mouse brain, human small intestine, and rat heart tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to a sequence from the C-terminal cytoplasmic domain of human Somatostatin receptor type 5.
      EpitopeC-terminal cytoplasmic domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificitySomatostatin Receptor 5 (SSTR5). The antibody reacts with both natural and recombinant protein. Epitope location is cytoplasmic.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SSTR5
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~55 kDa observed. Target band size appears larger than the calculated molecular weight of 39.2 kDa due to glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in MCF-7 cell lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected Somatostatin Receptor Type 5 in 10 µg of MCF-7 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB5681-I 04055977298086

      Related Products & Applications

      Related Products

      Catalogue Number Description  
      AB15556-200UL Anti-Somatostatin Receptor Type 5 Antibody Show Pricing & Availability
      AB15556-50UL Anti-Somatostatin Receptor Type 5 Antibody Show Pricing & Availability
      AB9287 Anti-Somatostatin Receptor Type 5 Antibody Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies