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AB15138 Anti-Nogo Receptor Antibody

Anti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH.

Anti-Nogo Receptor Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Growth Cones & Axon Guidance UniProt Number: Q99PI8
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AB15138
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, R, HWB, IHCRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15138
      DescriptionAnti-Nogo Receptor Antibody
      Alternate Names
      • Reticulon-4 receptor
      • Nogo receptor
      • NgR
      • Nogo-66 receptor
      • Nogor
      • Rtn4r
      Background InformationAxons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord.
      References
      Product Information
      FormatPurified
      Control
      • Mouse cerebellum lysate
      PresentationPurified in PBS with 0.1% NaN3
      Quality LevelMQ100
      Applications
      ApplicationAnti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesNon-Lot Specific Tested Application 1:
      Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded)
      Biological Information
      ImmunogenRecombinant protein.
      EpitopeMature Form
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityCat. # AB15138 recognizes the mature form of Nogo Receptor.
      Species Reactivity
      • Mouse
      • Rat
      • Human
      Species Reactivity NoteMouse and rat. May react with human and primate based on sequence homology. Reactivity with other species has not been determined.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight~50.9 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely tested on mouse cerebellum lysate.
      Lot Specific Tested Application 1: Western Blot
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB15138 04053252625527

      Documentation

      Anti-Nogo Receptor Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Nogo Receptor Antibody Certificates of Analysis

      TitleLot Number
      Anti-Nogo Receptor - 1977609 1977609
      Anti-Nogo Receptor - 3172613 3172613
      Anti-Nogo Receptor - 3498495 3498495
      Anti-Nogo Receptor - 3548398 3548398
      Anti-Nogo Receptor - 3768098 3768098
      Anti-Nogo Receptor - LV1647009 LV1647009
      Anti-Nogo Receptor - NG1552292 NG1552292
      Anti-Nogo Receptor - NG1832151 NG1832151
      Anti-Nogo Receptor - NG1925396 NG1925396
      Anti-Nogo Receptor -2507757 2507757
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