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855014 NovaSyn®TG amino resin (130 µm)

Overview

Replacement Information
Description
Catalogue Number855014
Replaces01-64-0094
Brand Family Novabiochem®
Background InformationNovaSyn® TG amino resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol [1-3], in which the PEG chains have been terminally functionalized with an amino group. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis.

This resin can be easily converted into other supports suitable for use in SPOS by acylation with the appropriate carboxylic acid-containing linker. For example, Hutchins and Chapman [4] have coupled Riniker's HMPB linker to this resin and used it to prepare a range of ureas derived from glutamic acid.

The product number for this product was previously 01-64-0094.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore below +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂)lot specific result
This resin is a composite of low-crossed linked polystyrene and 3000-4000 M.W. polyethylene glycol, which has been terminally amino functionalised. 130µm beads.

Documentation

NovaSyn®TG amino resin (130 µm) SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] W. Rapp, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium', R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
  • [2] L. Zhang, et al. in 'Peptides 1990, Proc. 21st European Peptide Symposium', E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp. 196.
  • [3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
  • [4] S. M. Hutchins & K. T. Chapman (1994) Tetrahedron Lett., 35, 4055.