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855013 NovaSyn®TG Sieber resin

Novabiochem®

NovaSyn®TG Sieber resin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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855013
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Overview

Replacement Information
Description
Catalogue Number855013
Replaces01-64-0092
Brand Family Novabiochem®
Alternate Names
  • 9-Fmoc-amino-xanthen-3-yloxy TG resin
Background InformationNovaSyn® TG Sieber resin consists of 130 μm NovaSyn® TG bromo resin derivatized with Sieber's xanhydrylamine linker [1, 2]. This resin is ideal for the Fmoc SPPS of partially protected peptide amide fragments. Cleavage from this support is effected by treatment with 1% TFA in DCM, conditions that leave most standard side-chain protecting groups intact.

This resin can be reductively alkylated and used to prepare secondary carboxamides [3]. It can also be employed to produce protected peptide fragments in which the C-terminal carboxylic acid group is blocked as a hydroxymethylphenoxy-β-alaninamide ester [4].

The product number for this product was previously 01-64-0092.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)light yellow to yellow to beige
Appearance of substance (visual)beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF)0.10 - 0.25 mmol/g
Swelling Volume (in DMF)lot specific result
The polymer matrix is NovaSyn TG resin (130µm)

Documentation

NovaSyn®TG Sieber resin SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] P. Sieber (1987) Tetrahedron Lett., 28, 2107.
  • [2] C. Somlai, et al. in 'Peptides 1992, Proc. 22nd European Peptide Symposium', C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 198.
  • [3] W. C. Chan, et al. (1995) J. Chem. Soc., Chem. Commun., 1475.
  • [4] W. C. Chan, et al. (1995) J. Chem. Soc., Chem. Commun., 589.