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575001 α-Synuclein, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NACP

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575001
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Overview

Replacement Information

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575001-200UG
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      		 Plastic ampoule 200 μg
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      575001-UG
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          Description
          OverviewRecombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140). This enzyme has been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.
          Catalogue Number575001
          Brand Family Calbiochem®
          SynonymsNACP
          References
          ReferencesKahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
          Kim, J. 1997. Mol. Cells 7, 78.
          Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
          Jakes, R., et al. 1994. FEBS Lett. 345, 27.
          Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.
          Product Information
          FormLiquid
          FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          575001-200UG 04055977189193
          575001-UG 04061839404847

          Documentation

          α-Synuclein, Human, Recombinant, E. coli SDS

          Title

          Safety Data Sheet (SDS) 

          α-Synuclein, Human, Recombinant, E. coli Certificates of Analysis

          TitleLot Number
          575001

          References

          Reference overview
          Kahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
          Kim, J. 1997. Mol. Cells 7, 78.
          Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
          Jakes, R., et al. 1994. FEBS Lett. 345, 27.
          Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2008 RFH
          SynonymsNACP
          DescriptionRecombinant, human α-synuclein expressed in E. coli. An acidic neuronal protein consisting of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. Also reported to be an important regulatory component of vesicular transport in neuronal cells. The apparent molecular weight by SDS-PAGE is ~19-20 kDa.
          FormLiquid
          FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.
          Concentration Label Please refer to vial label for lot-specific concentration
          Purity≥95% by SDS-PAGE
          Storage Avoid freeze/thaw
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesKahle, P.J, et al. 2001. Am. J. Pathol. 159, 2215.
          Kim, J. 1997. Mol. Cells 7, 78.
          Paik, S.R. 1997. Arch. Biochem. Biophys. 344, 325.
          Jakes, R., et al. 1994. FEBS Lett. 345, 27.
          Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 11282.